| 应用 |
A calcium channel protein inhibitor and blocker. |
| 产品介绍 |
Lacidipine 是一种L-型钙离子通道抑制剂。 |
| 备注 |
Lacidipine (Lacipil, Motens) is a L-type calcium channel blocker. |
| 生化机理 |
Lacidipine is a long-acting calcium antagonist that is used in the management of hypertension. Lacidipine is a L-type Ca(2+) channel blocker belonging to 1,4-dihydropyridine class. Also, Lacidipine inhibits ryanodine receptors on the ER membrane that enhances folding, trafficking and lysosomal activity of ERAD (ER-associated degradation) misfolded lysosomal glucocerebrosidase (GS). |
| 别名 |
拉西地平; (E)-4-[2-[3-(1,1-二甲基乙氧基)-3-氧代-1-丙烯基]苯基]-1,4-二氢-2,6-二甲基-3,5-吡啶二羧酸二乙酯;Lacipil; Motens;(E)-4-[2-[3-(1,1-Dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester |
