Safinamide Mesylate
面议
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分子式 C17H19FN2O2·CH4O3S 分子量398.45 MDL号 MFCD15145475 属性 溶解性 DMSO 80 mg/mL Water 80 mg/mL Ethanol 13 mg/mL 存贮条件 储存温度 2-8°C
| 货号 | CAS号 | 操作 |
|---|---|---|
| S129877-5mg | 202825-46-5 | 询底价 |
| S129877-10mg | 202825-46-5 | 询底价 |
| S129877-50mg | 202825-46-5 | 询底价 |
耗材描述
- 分子式 C17H19FN2O2·CH4O3S
- 分子量398.45
- MDL号 MFCD15145475
属性
| 溶解性 |
|
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | A potent and selective MAO-B inhibitor. |
| 产品介绍 | Safinamide Mesylate是Safinamide的甲磺酸盐，是一种选择性的且可逆的MAO-B抑制剂，IC50为98 nM，比作用于MAO-A选择性高5918倍。 |
| 备注 | Safinamide Mesylate is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. Phase 3. |
| 生化机理 | Safinamide is a dopamine reuptake inhibitor by being a highly selective inhibitor of MAO-B (IC50 = 98 nM. Additionally, this compound has a high affinity for Na+ channels (IC50 = 8 μM. |
| 别名 | 沙芬酰胺甲磺酸盐;Safinamide mesylate salt;(S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide; (S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]propanamide; FCE-26743; PNU-151774E; NW-1015 |
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