Tigecycline-分析测试百科网

Tigecycline

面议

品牌：阿拉丁
厂商性质：生产商
产地类别：国产
产地：上海
货期：现货
服务地域：全国
规格：5
近期咨询：0

分子式 C29H39N5O8 分子量585.65 Beilstein号 EC号 MDL号 PubChem编号属性敏感性对热敏感溶解性 DMSO 100 mg/mL Water 100 mg/mL Ethanol <1 mg/m

上海阿拉丁生化科技股份有限公司

上海阿拉丁生化科技股份有限公司

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货号	CAS号	操作
E129449-250mg	220620-09-7	询底价
E129449-5g	220620-09-7	询底价
E129449-50mg	220620-09-7	询底价
E129449-10mg	220620-09-7	询底价
E129449-1g	220620-09-7	询底价

耗材描述

分子式 C₂₉H₃₉N₅O₈
分子量585.65
Beilstein号
EC号
MDL号
PubChem编号

属性

敏感性	对热敏感
溶解性	DMSO 100 mg/mL Water 100 mg/mL Ethanol <1 mg/mL
存贮条件	储存温度-20°C

描述

应用	Tigecycline 是一种广谱的甘氨酰环素抗生素,对 E. coli (MG1655 菌株) 的平均抑制浓度 (MIC) 约为 125 ng/ mL。对 Acinetobacter baumannii (A. baumannii) 的 MIC50 和 MIC90 分别为 1 和 2 mg/L。
产品介绍	Tigecycline is a broad spectrum glycylcycline antibiotic. Tigecycline is bacteriostatic. It inhibits protein synthesis through the binding of the 30S ribosomal subunit of bacteria. This blocks entry of Aminoacyl-tRNA into the A site of the ribosome during translation. Tigecycline is active against resistant strains of gram-positive and gram-negative bacteria, avoiding the two most common mechanisms of resistance to the tetracycline antimicrobials: tetracycline efflux pump proteins and ribosomal protection proteins.
备注	Tigecycline is a glycylcycline antibiotic.
生化机理	Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation.
别名	替加环素;(4S,4aS,5aR,12aS)-4,7-双(二甲氨基)-9-[(叔丁基氨基)乙酰胺基]-3,10,12,12a-四羟基-1,11-二氧代-1,4,4a,5,5a,6,11,12a-八氢并四苯-2-甲酰胺;9-叔丁基甘氨酰氨基米诺环素 ;9-t-Butylglycylamido-minocycline; TBG-MINO; Tigecyclin; Tygacil;(4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide;9-tert-Butylglycylamidominocycline

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