Anastrozole-分析测试百科网

Anastrozole

面议

品牌：阿拉丁
厂商性质：生产商
产地类别：国产
产地：上海
货期：现货
服务地域：全国
规格：5
近期咨询：1

分子式 C17H19N5 分子量293.37 属性溶解性 Soluble in chloroform, methanol, ethanol (59 mg/ml at 25 °C), DMSO (59 mg/ml at 25 °C), an

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上海阿拉丁生化科技股份有限公司

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货号	CAS号	操作
A126470-25g	120511-73-1	询底价
A126470-500mg	120511-73-1	询底价
A126470-100mg	120511-73-1	询底价
A126470-5g	120511-73-1	询底价
A126470-1g	120511-73-1	询底价

耗材描述

分子式 C₁₇H₁₉N₅
分子量293.37

属性

溶解性	Soluble in chloroform, methanol, ethanol (59 mg/ml at 25 °C), DMSO (59 mg/ml at 25 °C), and DMF (~14 mg/ml).
存贮条件	储存温度-20°C

描述

产品介绍	Anastrozole is known to inhibit the CYP19 enzyme (aromatase, IC50 = 15 nM) that converts androgens to estrogens. Anastrozole has been seen to reversibly bind to the CYP19 enzyme through competitive inhibition.
备注	Anastrozole is a third-generation nonsteroidal selective aromatase inhibitor.
生化机理	Anastrozole is a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM) that has no discernible effect on adrenocorticoid hormone synthesis. Anastrozole reduces plasma estrogen levels and exhibits antitumor activity in vivo. Orally active.
别名	阿那曲唑;ICI-D1033;2;2"-[5-(1H-1;2;4-Triazol-1-ylmethyl)-1 3-Phenylene]bis(2-methyl-propiononitrile、 Arimidex;ZD1033 a,a,a′,a′-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile

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