AS-604850
面议
- 阿拉丁
- 生产商
- 国产
- 上海
- 现货
- 全国
- 3
- 1
分子式 C11H5F2NO4S 分子量285.22 Beilstein号 EC号 MFCD19705528 MDL号 MFCD19705528 PubChem编号 24724381 属性 溶解性 Soluble in DMSO (>1
| 货号 | CAS号 | 操作 |
|---|---|---|
| A129517-100mg | 648449-76-7 | 询底价 |
| A129517-25mg | 648449-76-7 | 询底价 |
| A129517-5mg | 648449-76-7 | 询底价 |
耗材描述
- 分子式 C11H5F2NO4S
- 分子量285.22
- Beilstein号
- EC号 MFCD19705528
- MDL号 MFCD19705528
- PubChem编号 24724381
属性
| 溶解性 | Soluble in DMSO (>10 mg/ml), water (<2 mg/ml), acetonitrile (6 mg/ml), methanol (9 mg/ml), and 100% ethanol. |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 | An ATP-competitive inhibitor of PI 3-kinase γ. |
| 产品介绍 | AS-604850是一种选择性的，ATP竞争性的PI3Kγ抑制剂，IC50为250 nM，作用于PI3Kγ比作用于PI3Kδ/β选择性高80倍以上，作用于PI3Kγ比作用于PI3Kα选择性高18倍。 |
| 备注 | AS-604850 is a selective, ATP-competitive PI3Kγ inhibitor with IC50 of 250 nM, over 80-fold selectivity for PI3Kγ than PI3Kδ/β, and 18-fold more selective for PI3Kγ than PI3Kα. |
| 生化机理 | AS-604850 is a potent, cell permeable and ATP-competitive inhibitor of PI 3-kinase γ (PI(3)Kγ). AS-604850 also exhibits selectivity over other PI 3-kinase isoforms. AS-604850 is an inhibitor of PI 3-kinase and PI 3-kinase p55 γ, PI 3-kinase p110 α and PI 3-kinase p85 α. |
| 别名 | AS 604850; 5-[(2,2-二氟-1,3-苯并二恶茂-5-基)亚甲基]噻唑烷-2,4-二酮; 5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione ;PI3Kγ inhibitor;AS 604850 |
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