Batimastat
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分子式 C23H31N3O4S2 分子量477.64 Beilstein号 EC号 MDL号 MFCD00866533 PubChem编号 属性 溶解性 DMSO 96 mg/mL Water <1 mg/mL Ethanol <
| 货号 | CAS号 | 操作 |
|---|---|---|
| B125646-1mg | 130370-60-4 | 询底价 |
| B125646-5mg | 130370-60-4 | 询底价 |
| B125646-25mg | 130370-60-4 | 询底价 |
耗材描述
- 分子式 C23H31N3O4S2
- 分子量477.64
- Beilstein号
- EC号
- MDL号 MFCD00866533
- PubChem编号
属性
| 溶解性 |
|
| 存贮条件 | 储存温度-20°C |
描述
| 应用 | Batimastat was used to study the role of MMP in proteolytic release of EGF in human follicular thyroid carcinoma cell line FTC-133. |
| 产品介绍 | Batimastat 是一种有效的广谱 MMP 抑制剂，作用于 MMP-1，MMP-2，MMP-9，MMP-7 和 MMP-3，IC50 分别为 3，4，4，6 和 20 nM。 |
| 备注 | Batimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3 with IC50 of 3 nM, 4 nM, 4 nM, 6 nM and 20 nM, respectively. |
| 生化机理 | Batimastat is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor. Batimastat is hydroxamate-type inhibitor of matrix metalloproteinases (MMP).It inhibits the growth and spread of lung tumors,breast cancer regrowth and human colon tumor growth and spread in mouse models. Batimastat reduces MMP-mediated vascular dysfunction and vessel wall damage and enhances the sealing ability and bond strength of dental adhesives. |
| 别名 | 巴马司他; (2S,3R)-N-羟基-N'-[(2S)-1-甲基氨基-1-氧代-3-苯基丙-2-基]-3-异丁基-2-(噻吩-2-基硫甲基)丁二酰胺;BB-94; BB 94; BB94; (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide |
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