PQ 401
面议
- 阿拉丁
- 生产商
- 国产
- 上海
- 现货
- 全国
- 2
- 1
分子式 C18H16ClN3O2 分子量341.79 MDL号 MFCD00160558 PubChem编号 24724567 属性 溶解性 25°C: DMSO 32 mg/mL (93.62 mM);Water <1 mg/mL
| 货号 | CAS号 | 操作 |
|---|---|---|
| P125823-50mg | 196868-63-0 | 询底价 |
| P125823-10mg | 196868-63-0 | 询底价 |
耗材描述
- 分子式 C18H16ClN3O2
- 分子量341.79
- MDL号 MFCD00160558
- PubChem编号 24724567
属性
| 溶解性 | 25°C: DMSO 32 mg/mL (93.62 mM);Water <1 mg/mL (<1 mM);Ethanol <1 mg/mL (<1 mM) |
| 存贮条件 | 储存温度2-8℃ |
描述
| 应用 | An inhibitor of IGF-1R autophosphorylation. |
| 产品介绍 | PQ 401抑制IGF-1R区域自磷酸化，IC50为低于1 μM。 |
| 备注 | PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM. |
| 生化机理 | PQ401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation. The mechanism of inhibition likely involves indirect blocking of ATP binding. PQ401 also decreases IGF-1R-dependent tumor cell growth in vitro. |
| 别名 | N-(5-氯-2-甲氧基苯基)-N'-(2-甲基-4-喹啉基)脲;PQ 401;PQ-401;IGF-1R Inhibitor II;N-(5-Chloro-2-methoxyphenyl)-N'-(2-methyl-4-quinolinyl)-urea |
猜你喜欢
感兴趣产品