Rapamycin-分析测试百科网

Rapamycin

面议

分子式 C51H79NO13 分子量914.172 Beilstein号 EC号 MDL号 MFCD00867594 PubChem编号属性敏感性对热敏感溶解性 Soluble in DMSO at 50mg/ml or metha

400-6699-117 转1000

耗材描述

敏感性	对热敏感
溶解性	Soluble in DMSO at 50mg/ml or methanol at 25mg/mlSoluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water.
存贮条件	储存温度 -20°C,充氩保存

应用	Rapamycin 是一种特异性的 mTOR 抑制剂，IC50 为 0.1 nM。
生化机理	A macrocyclic triene antibiotic that binds to and inhibits the molecular target of rapamycin (mTOR). It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR). Rapamycin is a potent immunosuppressant and has anticancer activity.
别名	西罗莫司;AY 22989;雷帕霉素Sirolimus;23,27-?Epoxy-?3H-?pyrido[2,1-?c]?[1,4]?oxaazacyclohentriacontine;AY 22989