耗材描述

• 分子式 C₃₀H₄₈O₃
• 分子量456.70
• Beilstein号 2228563
• EC号 201-034-0
• MDL号 MFCD00009621
• PubChem编号 24889274

属性

熔点	292 °C
旋光率	+58.0 to +65.0 deg(C=1, Pyridine)
敏感性	对空气敏感
存贮条件	存储温度2-8℃;充氩保存
密度	1.0900

描述

应用	An anti-angiogenic and anti-proliferative agent
产品介绍	存在于天然植物中的一种三萜类化合物。不溶于水，溶于2%酒精的NaOH，溶于热冰醋酸，中度溶于丙酮，微溶于醇、醚、氯仿和二硫化碳。
生化机理	Ursolic Acid, a naturally occurring triterpenoid, has been noted to demonstrate anti-angiogenic and anti-proliferative properties. Mechanistic studies suggest that this compound down-regulates MMP-2 and uPA expression in cells via inhibition of Akt, JNK, mammalian target of Rapamycin phosphorylation, and levels of NFκB protein in the nucleus. Other experiments have shown that Ursolic Acid may improve blood glucose, glucose tolerance, insulin tolerance, glycosylated hemoglobin, and plasma leptin levels in diabetic murine models. Additionally, this agent displays a capacity to induce cell cycle arrest and apoptosis through activation of p53 pathway and Bax protein, as well as down-regulation of Bcl-2.
别名	乌苏酸;乌索酸;3-羟基-(3β)-乌索-12-烯-28-酸;3β-Hydroxy-12-ursen-28-ic acid

个人防护设备	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK德国	3
安全声明（欧洲）	S24/25

猜你喜欢

• 

  新利司他

• 

  氯尼辛

• 

  洛索洛芬钠二水合物

• 

  Z824607-bulk (2'Z,3'E)-6-溴靛玉红-3'-肟,99%

• 

  N824615-25mg N-[4-[[4-(二甲基氨基)-1-哌啶基]羰基]苯基]-N’-[4-[4,6-二(4-吗啉基)-1,3,5-三嗪-2-基]苯基]脲,99%

• 

  甲氧氯普胺

• 

  N824615-5mg N-[4-[[4-(二甲基氨基)-1-哌啶基]羰基]苯基]-N’-[4-[4,6-二(4-吗啉基)-1,3,5-三嗪-2-基]苯基]脲,99%

• 

  T824567-25mg (Z)-1-(3-乙基-5-甲氧基-2,3-二羟基并噻唑-2-亚基)丙酮,99%

• 

  (R)-(-)-Rolipram

• 

  D806401-1g 6,7-二甲氧基香豆素,98%

感兴趣产品

• 熊果酸价格
• 熊果酸厂商
• 熊果酸规格