应用 |
Dodecylphosphocholine is often used as a detergent for membrane protein solubilization and purification.It has been shown to improve paracellular permeability of hydrophilic compounds by modulating the tight junctions. This may have implications on its use for oral or nasal drug delivery. |
产品介绍 |
Dodecylphosphocholine is a structural analog of lauroyl lysophosphatidylcholine that is more stable to hydrolytic degradation. |
生化机理 |
正十二烷基磷酸胆碱与 1,2-二肉豆蔻酰基-sn-甘油-3-磷酸胆碱(DMPC)结合可用于膜模拟 bicelle 系统,用于基于方向的膜蛋白研究。它在膜胶束结构中提供了两性离子表面 |
别名 |
DPC;Fos-Choline-12;FOS12;FC-12;2-[[(十二烷氧基)羟基亚膦酰]氧基]-N,N,N-三甲基-乙铵内盐
;DPC;Fos-Choline-12;FOS12;FC-12;2-[[(Dodecyloxy)Hydroxyphosphinyl]Oxy]-N,N,N-Trimethyl-Ethanaminium Inner Salt;Dodecyl 2-Trimethylammonioethyl Phosphate;Lauryl 2-Trimethylammonioethyl Phosphate; |