| 应用 |
Coenzyme A trilithium salt has been used:
1.in standard curve generation in the kinetic assay of acetyltransferase Gcn5 acylation
2.as a cofactor in JNADH and JNADPH production assay
3.in the labeling of Alexa647 (AF647) probe |
| 产品介绍 |
Coenzyme A (CoA) is synthesized from phosphopantothenate by the action of enzyme pantothenate kinase and is the master regulator. |
| 生化机理 |
Coenzyme A (CoA, CoASH, HSCoA) is a coenzyme that facilitates enzymatic acyl-group transfer reactions and supports the synthesis and oxidation of fatty acids. CoA is involved in the mechanisms of a wide variety of enzymes. Acyl CoA accumulation is implicated in metabolic disorders and may indirectly lead to the pathogenesis associated with carbon-induced mitochondrial stress heart failure, diabetes and obesity. |
| 别名 |
辅酶 A 三锂盐CoA-Li;CoA Li3;Coenzyme A trilithium salt |
