耗材描述

• 分子式 C₁₀H₁₂Na₃N₄O₁₄P₃
• 分子量574.11
• Beilstein号
• EC号
• MDL号 MFCD00084678
• PubChem编号 24895910

属性

存贮条件	贮存温度:-20°C

描述

应用	Inosine 5′-triphosphate (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. ITP may be used as a substrate to study the specificity and kinetics of nucleoside-5′-triphosphatase and ATPase. ITP is also used to study activation of various ATPases and GTPases. Inosine 5′-triphosphate trisodium salt has been used to investigate its influence on the chromosome aberration rate, the mitotic rate, sister-chromatid exchange (SCE) frequency, the proportion of first (X1), second (X2) and third (X3) division metaphases of human peripheral lymphocytes.
生化机理	Inosine 5′-triphosphate (ITP) has the ability to support the initiation of effector system. It can prevent guanosine 5′-triphosphate (GTP) hydrolysis, that is catalysed by transducin (TD). ITP can proficiently induce secretion in permeabilized cells than GTP. Instead of GTP, ITP can be used for the initiation and the elongation steps of reovirus transcription. ITP can also replace GTP in the activation of G-protein.
别名	;ITP

WGK德国	1
风险声明 (欧洲)	R36/37/38
安全声明（欧洲）	S26

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