| 应用 |
β-Nicotinamide adenine dinucleotide phosphate hydrate is suitable for use in:
· the measurement of Glucose-6-phosphate dehydrogenase activity
· the Cytochrome P450 3A4 assay as a part of NADPH-regenerating system
· the Cytochrome P450 2D6 assay as a part of NADPH-regenerating system
· the determination of Glucose-6-phosphate content |
| 产品介绍 |
极易吸潮。溶于水和甲醇。较少溶于乙醇，几乎不溶于乙醚和乙酸乙酯。最大吸收波长260nm(ε18000)。 |
| 生化机理 |
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation.The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP). |
| 别名 |
β-烟酰胺腺嘌呤二核苷酸磷酸酯;烟酰胺腺嘌呤双核苷酸磷酸盐;辅酶Ⅱ;磷酸β-烟酰胺腺嘌呤二核苷酸;β-NADP;TPN;NADP;β-Triphosphopyridine Nucleotide;β-NADP; Coenzyme II; TPN; NADP; Triphosphopyridine nucleotide; Codehydrogenase II; |
