耗材描述

• 分子式 C₅H₉NO₃S
• 分子量163.19
• Beilstein号 1724426
• EC号 210-498-3
• MDL号 MFCD00004880
• PubChem编号 24277970

属性

熔点	109-111°C
旋光率	24 ° (JPC Method)
溶解性	Soluble in water (100 mg/ml) with heating and obtained a clear, colorless solution, 1 in 2 of ethanol, DMSO (≥33 mg/ml) at 25 °C, hot isopropyl alcohol, methyl acetate, ethyl acetate and methanol. Practically insoluble in chloroform, and ether.
存贮条件	储存温度2-8℃

描述

应用	An antioxidant mucolytic acetylated amino acid.
产品介绍	N-Acetyl-L-cysteine is an acetylated amino acid with antioxidant and mucolytic properties. These two activities have made N-Acetyl-L-cysteine particularly relevant in cystic fibrosis studies, where the antioxidant/reducing character of the compound is described to ameliorate the characteristic systemic redox imbalance state of cystic fibrosis and the mucolytic properties of the compound are shown to impede upon the congestion and inflammation correlated to this redox state. As a mucolytic, N-Acetyl-L-cysteine serves to dissipate disulfide bonds across mucoproteins, loosening and clearing the viscosity of sputum. N-Acetyl-L-cysteine shows complimentary action to glutathione, both demonstrating antioxidant activity through their thiol functionality, and both are shown to protect against peroxidative stress related to septic shock. N-Acetyl-L-cysteine has also been shown to induce apoptosis in vascular smooth muscle cells, indicating that these cells respond differently to changes in reduction-oxidation state than other tissues that are normally protected by the presence of antioxidants. This observation in vascular smooth muscle cells indicates N-Acetyl-L-cysteine as an interventional tool upon arteriosclerotic proliferation of these cells.
别名	乙酰半胱氨酸;N-乙酰半胱氨酸;D-3-(2-萘基)-丙氨酸;LNAC;NAC;Ac-Cys-OH; LNAC; N-Acetyl-3-mercaptoalanine; NAC

Merck Index	88
个人防护设备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
RTECS	HA1660000
WGK德国	2
安全声明（欧洲）	S24/25

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