酒石酸酮色啉盐
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分子式 C22H22FN3O3·C4H6O6 分子量545.51 Beilstein号 EC号 281-062-8 MDL号 MFCD00084651 PubChem编号 24278121 属性 熔点 183-186°C 敏感性 对湿度敏感
| 货号 | CAS号 | 操作 |
|---|---|---|
| K107929-250mg | 83846-83-7 | 询底价 |
| K107929-500mg | 83846-83-7 | 询底价 |
| K107929-50mg | 83846-83-7 | 询底价 |
| K107929-10mg | 83846-83-7 | 询底价 |
耗材描述
- 分子式 C22H22FN3O3·C4H6O6
- 分子量545.51
- Beilstein号
- EC号 281-062-8
- MDL号 MFCD00084651
- PubChem编号 24278121
属性
| 熔点 | 183-186°C |
| 敏感性 | 对湿度敏感 |
| 溶解性 | Soluble in DMSO at 50mg/ml. Also soluble in 0.1N HCl (6mg/ml) or in ethanol (3.3mg/ml) |
| 存贮条件 | 储存温度 2-8°C |
描述
| 应用 |
选择性5-HT2 5-羟色胺(serotonin) 受体拮抗剂。 Ketanserin (+)-tartrate salt has been used: · as a 5HT2A antagonist in Krebs-Henseleit buffer solution · for hormonal treatment to study the effects of exogenous manipulation of different hormonal systems in interaction with parasite infection on client′s behavior · to study the behavioural changes of incision pain rats |
| 生化机理 | Selective 5-HT2 serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction |
| 别名 | 酮舍林酒石酸盐;酮色林 (+)-酒石酸盐;3-（2- [4-（4-氟苯甲酰基）-1-哌啶基]乙基）-2,4（1H，3H）喹唑啉二酮 (+)-酒石酸盐; R 41468 (+)-酒石酸盐;R 41468 (+)-tartrate salt 3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt |
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