Arg-Gly-Asp-Ser-分析测试百科网

Arg-Gly-Asp-Ser

面议

品牌：阿拉丁
厂商性质：生产商
产地类别：国产
产地：上海
货期：现货
服务地域：全国
规格：3
近期咨询：0

分子式 C15H27N7O8 分子量433.42 Beilstein号 EC号 MDL号 MFCD00076452 PubChem编号 24891220 属性存贮条件储存温度-20°C 密度 1.6500 //decorateTable

上海阿拉丁生化科技股份有限公司

上海阿拉丁生化科技股份有限公司

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货号	CAS号	操作
A101721-2mg	91037-65-9	询底价
A101721-5mg	91037-65-9	询底价
A101721-25mg	91037-65-9	询底价

耗材描述

分子式 C₁₅H₂₇N₇O₈
分子量433.42
Beilstein号
EC号
MDL号 MFCD00076452
PubChem编号 24891220

属性

存贮条件	储存温度-20°C
密度	1.6500

描述

应用	A tetrapeptide that supports fibroblast attachment and inhibits fibronectin binding.
产品介绍	Arg-Gly-Asp-Ser.It is a key component of the cell attachment domain of fibronectin. The RGDS sequence was found initially to promote the attachment of rat kidney fibroblasts (NRKcells) to fibronectin and synthetic fibronectin peptides coupled to protein-coated plastic. Further investigation indicated that the free RGDS peptide inhibited the attachment of NRK cells to fibronectin coated substrates. The RGDS sequence has been shown to occur in several other proteins, such as the λ receptor on E. coli and the Sindbis coat protein. RGDS is also a target sequence for spirochete adherence of the syphilis bacterium Treponema pallidum.It has been shown to block fibrinogen-induced aggregation of intact erythrocytes and specific binding of fibrinogen to erythrocyte membranes. The effect of RGDS on transforming growth factor β1 (TGFβ1) mRNA expression and secretion in cultured human mesangial cells has been investigated. RGDS has been utilized in a study of integrin-mediated signal transduction in cultured cells from the sponge Suberites domuncula. RGDS has been demonstrated to mitigate the binding of Mycobacterium tuberculosis to murine alveolar macrophages.
别名	RGDS;L-精氨酰甘氨酰-L-alpha-天冬氨酰-L-丝氨酸;RGDS;Arginyl-glycyl-aspartyl-serine;H-Arg-Gly-Asp-Ser-OH;Fibronectin Inhibitor;L-Arginylglycyl-L-alpha-aspartyl-L-serine

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