姜黄素
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分子式 C21H20O6 分子量368.38 Beilstein号 2306965 EC号 207-280-5 MDL号 MFCD00008365 PubChem编号 24892408 属性 熔点 183°C 溶解性 Soluble in
| 货号 | CAS号 | 价格 | 操作 |
|---|---|---|---|
| C140600-100g | 458-37-7 | 面议 | 询底价 |
| C140600-25g | 458-37-7 | 面议 | 询底价 |
| C140600-5g | 458-37-7 | 面议 | 询底价 |
| C110685-20mg | 458-37-7 | ￥199.00 | 询底价 |
耗材描述
- 分子式 C21H20O6
- 分子量368.38
- Beilstein号 2306965
- EC号 207-280-5
- MDL号 MFCD00008365
- PubChem编号 24892408
属性
| 熔点 | 183°C |
| 溶解性 | Soluble in acetone, dimethylsufoxide, ethanol and dimethyl formamide. Insoluble in water. |
| 存贮条件 | 储存温度 -20°C |
| 密度 | 0.9300 |
描述
| 应用 |
酸碱指示剂，pH7.8(黄)～9.2(红棕)。显色反应测铍、锆和镁，硼酸盐和试剂。 一种天然酚性物质，抗肿瘤和消炎物质，并具有抗氧化特性，能诱导癌细胞凋亡。 Curcumin has been used: · to measure its antibacterial activity in vitro · to determine its preventative effects for Alzheimer′s disease (AD) in mice · as a bifunctional agent for generation and validation of the erythroid 2-related factor 2 (Nrf2) reporter system · to study its in vitro inhibitory effects on human liver glucuronidation activity · to evaluate the effects of curcumin on Parkinson′s disease (PD)-like phenotypes |
| 产品介绍 | 易溶于冰乙酸，能溶于醇，不溶于醚带淡绿色荧先，溶于碱呈红棕色，加酸于碱液后变为淡黄色并析出姜黄素沉淀，溶于浓硫酸带黄红色，不溶于水。 |
| 生化机理 | A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity.1 Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope. |
| 别名 | 克扣明;姜黄色素;川芎内酯 B;1,7-双(4-羟基-3-甲氧基苯基)-1,6-庚二烯-3,5-二酮;(E,E)-1,7-双(4-羟基-3-甲氧基苯基)-1,6-庚二烯-3,5-二酮;Natural Yellow 3;Diferuloylmethane;Diferulylmethane;(E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione |
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