桦木脑
面议
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分子式 C30H50O2 分子量442.72 Beilstein号 EC号 207-475-5 MDL号 MFCD00016802 PubChem编号 24892156 属性 熔点 256-257°C 存贮条件 储存温度:2-8°C //d
| 货号 | CAS号 | 价格 | 操作 |
|---|---|---|---|
| B129170-1g | 473-98-3 | 面议 | 询底价 |
| B129170-25g | 473-98-3 | 面议 | 询底价 |
| B129170-5g | 473-98-3 | 面议 | 询底价 |
| B129170-100g | 473-98-3 | 面议 | 询底价 |
| B129169-20mg | 473-98-3 | ￥135.00 | 询底价 |
耗材描述
- 分子式 C30H50O2
- 分子量442.72
- Beilstein号
- EC号 207-475-5
- MDL号 MFCD00016802
- PubChem编号 24892156
属性
| 熔点 | 256-257°C |
| 存贮条件 | 储存温度:2-8°C |
描述
| 应用 | A triterpene with a pentacyclic ring structure.It can be used in the preparation of betulinic acid，which shows anti-HIV, antimalarial and anti-inflammatory activities. |
| 生化机理 | Betulin is a triterpene with a pentacyclic ring structure and hydroxyl groups in positions C3 and C28. Studies indicate that Betulin can effect intracellular signaling in ethanol-induced liver cells via inhibiting ROS, TNFα and TNFβ. In human cancer cells Betulin can induce mitochondrial cytochrome C release in human cancer cells, which results in apoptosis. Alternate studies on mice show that Betulin binds to melanocortin receptors and antagonizes the release of cAMP generation in mouse melanoma cells. Furthermore, Betulin has protective effects against cadmium induced apoptosis in human hepatoma cell lines. This occurs by inhibiting the activation of ROS, blocking Bid activation and suppressing the mitochondrial pathway. |
| 别名 | 白桦脂醇;桦木醇Lup-20(29)-ene-3β,28-diol |
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