耗材描述

• 分子式 C₂₀H₁₄ClNO₄ · xH₂O
• 分子量367.78(anhydrous basis)
• Beilstein号
• EC号
• MDL号 MFCD00012126
• PubChem编号

属性

熔点	277-280°C
溶解性	Soluble in methanol, water (slightly), DMSO (10 mM), and ethanol (5 mM).

描述

应用	一个具有抗菌，消炎，抗氧化性能的天然产物。有抑制肿瘤细胞株扩增和促凋亡作用。 A benzophenanthridine alkaloid and potent, noncompetitive Na+/K+-and Mg2++-ATPase inhibitor
产品介绍	Sanguinarine chloride is a benzophenanthridine alkaloid and potent, noncompetitive sodium/Potassium-ATPase Protein Inhibitors (Na+/K+ ATPase) inhibitor with anticancer properties. This product has been observed to induce apoptosis in cultured C6 rat glioblastoma cells potentially via a downregulative ability of extracellular singal-regulated and Akt signaling pathways. It is reported that sanguinarine also inhibits protein phosphatase 2C (PP2) and induces human promyelocytic leukemia cell line HL60 apoptosis through the phosphorylation of p38, a PP2Cα substrate associated with caspase-3/7 activity. This compound posesses antimicrobial and anti-plaque qualities. Sanguinarine chloride is an inhibitor of MKP-1 and PP2. Isolated from the leaves and stems of Macleaya cordata and M. microcarpa.
备注	CAS Number: 5578-73-4 (anhydrous),Formula weight and CAS # are for anhydrous basis.
别名	氯化血根碱;血根碱盐酸盐

猜你喜欢

• 

  松果菊苷

• 

  盐酸石蒜碱

• 

  γ-亚麻酸甲酯

• 

  芦荟甙

• 

  油酸

• 

  二氢辣椒碱

• 

  橄榄苦苷

• 

  木犀草苷

• 

  正辛酸

• 

  水杨酸

感兴趣产品

• 血根碱水合物价格
• 血根碱水合物厂商
• 血根碱水合物规格