High Resolution, High-Capacity Cation-Exchange Column for the Separation of Small Polar Amines

Attain the optimal combination of chromatographic speed and resolution using the new Thermo Scientific™ Dionex™ IonPac™ CS19-4µm cation-exchange column. This high capacity, high resolution capillary column provides excellent resolution of common cations, small polar amines and polyvalent amines in complex sample matrices. Compared to the previous Dionex IonPac CS19 column, the new ion-exchange column uses smaller resin particles for more efficient separations resulting in faster analysis, more accurate peak integration, and more reliable results.

The Dionex IonPac CS19-4µm carboxylate-functionalized cation-exchange column has similar selectivity to the Dionex IonPac CS19 column for the six common cations, small polar amines (including alkanolamines and methylamines) and moderately hydrophobic and polyvalent amines (including biogenic amines and alkyl diamines). Applications run on the Dionex IonPac CS19 column can be easily transferred to the Dionex IonPac CS19-4µm column with the benefit of increased peak resolution which provides more consistent results. The Dionex IonPac CS19-4µm column is available in three formats, standard bore (4 × 250 mm), microbore (2 × 250 mm), and capillary (0.4 × 250 mm). The capillary and microbore formats require less eluent thereby reducing operating costs.

• Increase speed, chromatographic resolution and quality of analytical results

• For analysis of amines including alkanolamines and methylamines in diverse sample matrices

• For analysis of moderately-hydrophobic amines including biogenic amines, alkyl diamines, and polyvalent amines

• Optimized for fast simple acidic gradient separations with minimal baseline shift

• High capacity allows routine analysis of high-ionic-strength samples

The Dionex IonPac CS19-4µm column is targeted for analysis of power plant waters treated with ammonium, morpholine, or ethanolamine; as well as chemical additives; chemical process solutions; scrubber solutions; personal care products; and food samples.

The smaller resin particles used in the Dionex IonPac CS19-4µm column produce increased backpressure. When operating the Dionex IonPac CS19-4µm microbore or capillary column at standard flow rate, an IC system capable of operating up to 3000 psi is sufficient. However, to take advantage of the fast runs, using elevated flow rates, a high pressure IC system, such as the Thermo Scientific Dionex ICS-5000⁺HPIC or Dionex ICS-4000 HPIC is required. The Dionex ICS-5000⁺HPIC system is required for standard operation of the Dionex IonPac CS19-4µm standard bore column.

Isocratic elution of the common cations plus ammonium using the Dionex IonPac CS19-4µm capillary column.

Fast gradient elution of Group I and Group II cations plus ammonium using the Dionex IonPac CS19-4µm column.

Gradient separation of common cations and biogenic amines using the Dionex IonPac CS19-4µm column.

Gradient separation of common cations and diamines using the Dionex IonPac CS19-4µm column.

Fast gradient separation of common cations and ethylamines using the Dionex IonPac CS19-4µm column with an increased flow rate and decreased column temperature.

Gradient separation of common cations and ethanolamines using the Dionex IonPac CS19-4µm column.

Isocratic elution of common cations and methylamines using the Dionex IonPac CS19-4µm column.