A127632-500mgAscomycin
面议
- 阿拉丁
- 生产商
- A127632-500mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C43H69NO12
- 分子量792.01
- Beilstein号
- EC号 200-835-2
- MDL号
- PubChem编号
属性
溶解性 | Soluble in DMSO (65 mg/ml), ethanol (50 mg/ml), and water (10-50 μM). |
存贮条件 | 储存温度-20°C |
描述
应用 | A potent immunosuppressive agent |
产品介绍 | Ascomycin(Immunomycin, FR-900520, FK520)是tacrolimus (FK506)的类似物,具有很强的免疫抑制剂。 |
生化机理 | When we used either CD4+CD8+ thymocytes or peripheral T cells activated by phorbol ester and ionomycin, the cell surface induction of CD5 was also partially blocked by CsA, FK-520 and rapamycin . Ascomycinalso had a 3-fold lower immunosuppressive potency in a popliteal lymph node hyperplasia assay, resulting in an equivalent therapeutic index consistent with a common mechanistic dependence on calcineurin inhibition |
别名 | 长川霉素;Immunomycin;FK 520;FR 900520;FR-900520;FR900520;FK-520;FK520 |
标识符号 | GHS02, GHS07 |
信号词 | Danger |
危害声明 | H225-H302 + H332-H319 |
警示性声明 | P210-P305 + P351 + P338 |
WGK德国 | 2 |
闪点(摄氏) | 35.6 °F |
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