V127611-5mgVX-222 (VCH-222, Lomibuvir)
面议
- 阿拉丁
- 生产商
- V127611-5mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C25H35NO4S
- 分子量445.63
属性
溶解性 |
|
存贮条件 | 储存温度-20°C |
描述
备注 | VX-222 (VCH-222) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L. Phase 2. |
生化机理 |
VX-222 is a small molecule non-nucleoside inhibitor of HCV NS5B polymerase that is being investigated for the treatment of hepatitis C virus infection. |
别名 | VCH222;2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-;VCH222;2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]- |
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