V125454-10mgVildagliptin (LAF-237)
面议
- 阿拉丁
- 生产商
- V125454-10mg
- 现货
- 全国
规格 |
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耗材描述
属性
溶解性 | Soluble in DMSO and Water |
存贮条件 | 储存温度-20°C |
描述
应用 | A CD26 inhibitor associated with immune response inhibition |
产品介绍 | Vildagliptin is a dipeptidyl peptidase-4 (CD26) inhibitor. CD26 activates serine proteases in immune/inflammatory cells. Vildagliptin also inhibits dipeptidyl-peptidase 8 (DPRP1) and dipeptidyl-peptidase 9 (DPRP2), which have been correlated to T cell activation and immune function, as well as diabetes and cancer regulation. |
备注 | Vildagliptin (LAF-237) inhibits DPP?4 with IC50 of 2.3 nM. |
生化机理 | Vildagliptin (LAF-237)抑制DPP?4,IC50为2.3 nM。 |
别名 | 维达列汀;维他列汀;(-)-(2S)-1-[[(3-羟基三环[3.3.1.1(3,7)]癸烷-1-基)氨基]乙酰基]吡咯烷-2-甲腈;LAF237;Galvus;NVP-LAF 237;Zomelis;1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)-2-Pyrrolidinecarbonitrile |
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