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MC1568
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| M127417-25mg | 852475-26-4 | 询价 |
| M127417-10mg | 852475-26-4 | 询价 |
产品介绍
- 分子量314.31
属性
| 溶解性 |
|
| 存贮条件 | 储存温度-20°C |
描述
| 产品介绍 | MC1568 |
| 备注 | MC1568 is a selective HDAC inhibitor for HDAC1A with IC50 of 100 nM. It is 34-fold more selective for HDAC1A than HDAC1B. |
| 生化机理 |
MC1568 is a class II (IIa) histone deacetylase (HDAC) inhibitor selective for HDAC4 and HDAC6 (IC50 = 220 nM). MC1568 exhibits tissue-selective inhibition between members of class II acetylases in vivo, particularly in skeletal muscle and the heart. MC1568 arrests myogenesis through the stabilization of myocyte enhancer factor 2D (MEF2D)-HDAC3/4 complex. Recent research showed that class II-specific HDACis may constitute a novel therapeutic strategy for improving the treatment of cancer. |
| 别名 | (E)-3-(4-((E)-3-(3-fluorophenyl)-3-oxoprop-1-enyl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide;(E)-3-(4-((E)-3-(3-fluorophenyl)-3-oxoprop-1-enyl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide |
MC1568信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于MC1568报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途