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微生物制剂
NBD-557
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| N125473-50mg | 333352-59-3 | 询价 |
| N125473-25mg | 333352-59-3 | 询价 |
| N125473-5mg | 333352-59-3 | 询价 |
产品介绍
- 分子式 C17H24BrN3O2
- 分子量382.3
属性
| 溶解性 | DMSO |
| 存贮条件 | 储存温度-20°C |
描述
| 产品介绍 | NBD-557是HIV-1抑制剂。 |
| 生化机理 | NBD-557, is small molecule organic compounds with drug-like properties. It showed potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels. A systematic study showed that NBD-557 target viral entry by inhibiting the binding of HIV-1 envelope glycoprotein gp120 to the cellular receptor CD4 but did not inhibit reverse transcriptase, integrase, or protease, indicating that they do not target the later stages of the HIV-1 life cycle to inhibit HIV-1 infection. NBD-557 potent inhibitors of both X4 and R5 viruses tested in CXCR4 and CCR5 expressing cell lines, respectively, indicating that its anti-HIV-1 activity is not dependent on the coreceptor tropism of the virus. |
| 别名 | NBD 557;NBD557;N-(4-溴苯基)-N'-(2,2,6,6-四甲基哌啶-4-基)草酰胺;NBD 557;NBD557;N-(4-Bromophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide;N1-(4-bromophenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide |
NBD-557信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于NBD-557报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途