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微生物制剂
Abacavir
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| A126552-1g | 136470-78-5 | 询价 |
| A126552-5g | 136470-78-5 | 询价 |
产品介绍
属性
| 溶解性 | 25°C: DMSO <1 mg/mL; Water 36 mg/mL; Ethanol<1mg/mL |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 |
Abacavir sulfate has been used as a compound to validate the P19C5 gastrulation in mouse. It has also been used to induces chromosomal double-strand breaks (DSBs) and kills adult T cell leukemia (ATL) cells. Abacavir sulfate has been used in the cytotoxicity to test its tumour promoting activity U937 cells. |
| 产品介绍 | Abacavir是强力的核苷类似物，为逆转录酶抑制剂。Abacavir exhibits antiviral activity. It is associated with myocardial infarction and fatal hypersensitivity reaction (HSR). |
| 生化机理 | Abacavir incorporated in the cells is converted to triphosphate containing guanine analog carbovir (CBV) and it favors the generation of higher double stranded breaks (DSBs). Abacavir sulfate is a Nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. |
| 别名 | 阿巴卡韦; (1S,4R)-4-[2-氨基-6-(环丙氨基)-9H-嘌呤-9-基]-2-环戊烯-1-甲醇;Ziagen;(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol |
Abacavir信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Abacavir报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途