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Dexpramipexole
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
阿拉丁 | 生产商 | 上海 | 现货 |
货号 | CAS号 | 操作 |
---|---|---|
D128003-10mg | 104632-28-2 | 询价 |
D128003-50mg | 104632-28-2 | 询价 |
D128003-100mg | 104632-28-2 | 询价 |
- 分子式 C10H17N3S
- 分子量211.33
属性
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
描述
产品介绍 | Dexpramipexole(KNS-760704)也叫R-(+)-Pramipexole,是神经保护剂,是弱的非麦角类多巴胺受体激动剂。 |
生化机理 |
Dexpramipexole, also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist. Dexpramipexole has been found to have neuroprotective effects and is being investigated for treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrial reactive oxygen species (ROS) production, inhibits the activation of apoptotic pathways, and increase cell survival in response to a variety of neurotoxins and β-amyloid neurotoxicity. Compared to the S-(-) isomer, Dexpramipexole has much lower dopamine agonist activity. |
别名 | KNS-760704;(R)-普拉克索;(R)-Pramipexole;R-(+)-Pramipexole;KNS-760704 |
Dexpramipexole信息由上海阿拉丁生化科技股份有限公司为您提供,如您想了解更多关于Dexpramipexole报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途