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Sulindac
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 操作 |
|---|---|---|
| S125148-1g | 38194-50-2 | 询价 |
| S125148-25g | 38194-50-2 | 询价 |
| S125148-100g | 38194-50-2 | 询价 |
| S125148-5g | 38194-50-2 | 询价 |
产品介绍
- 分子式 C20H17FO3S
- 分子量356.41
- EC号 253-819-2
- MDL号 MFCD00599589
- PubChem编号 24277737
属性
| 溶解性 | Soluble in water (0.05 mg/ml at 25 °C), methanol (50 mg/ml), ethanol (9 mg/ml at 25 °C), DMSO (71 mg/ml at 25 °C), and DMF (~ 30 mg/ml). |
描述
| 应用 | Treatment of human colorectal cancer cell lines induces MRP1 and MRP3 but not other members of the MRP family. Reported to significantly increase the cytotoxicity of the anthracyclines (doxorubicin, daunorubicin and epirubicin), as well as teniposide, VP- |
| 产品介绍 | Sulindac 是一种非甾体抗炎剂。 |
| 备注 | Sulindac (Clinoril) is a non-steroidal anti-inflammatory agent of the arylalkanoic acid class. |
| 生化机理 | Sulindac inhibits the NF-κB pathway. Sulindac is a non-steroidal anti-inflammatory drug. Sulindac reduces the level and activity of several cyclin-dependent kinases (CDKs) and induces apoptosis. Sulindac metabolizes to sulindac sulfide, a Cox (cyclooxygenase) inhibitor that represses ras signaling, and sulindac sulfone, an antitumor agent. Sulindac is an inhibitor of Cox-1 and Cox-2. |
| 别名 | 舒林酸; (Z)-5-氟-2-甲基-1-[4-(甲亚硫酰苯基)亚甲基]-1H-茚-3-醋酸;Aflodac; Sulinol; Sulreuma;MK-231;(Z)-5-Fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid; cis-5-Fluoro-2-methyl-1-[p-(methylsulfinyl)benzylidene]-indene-3-acetic acid |
Sulindac信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于Sulindac报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途