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催化和无机化学
卡铂
| 品牌 | 厂商性质 | 产地 | 货期 |
|---|---|---|---|
| 阿拉丁 | 生产商 | 上海 | 现货 |
产品参数
| 货号 | CAS号 | 价格 | 操作 |
|---|---|---|---|
| C110682-100mg | 41575-94-4 | ￥538.00 | 询底价 |
| C110682-1g | 41575-94-4 | ￥1,580.00 | 询底价 |
| C110682-250mg | 41575-94-4 | ￥999.00 | 询底价 |
| C110682-5g | 41575-94-4 | ￥3,860.00 | 询底价 |
产品介绍
- 分子式 C6H12N2O4Pt
- 分子量371.25
- Beilstein号
- EC号
- MDL号 MFCD00070464
- PubChem编号
属性
| 熔点 | >275℃ |
| 敏感性 | 对光敏感 |
| 溶解性 | Soluble in water. |
| 存贮条件 | 储存温度-20°C |
描述
| 应用 |
Carboplatin has been used: · in chemotherapy-induced thrombocytopenia mouse model and treatment · to induce cell death in a large subset of colorectal cancer cells · in the evaluation of cell proliferation and chemosensitivity · as a positive control for suppressed cell growth |
| 产品介绍 | Carboplatin is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of carboplatin was inspired from the efficacy of its progenitor, Cisplatin (sc-200896), the first of this class of antineoplastic agents. The action of this group of platinum-based compounds is primarily attributed to DNA adduct formation, however, these molecules also bind other biological molecules, including enzymes, which might play a role in their mechanism of action. |
| 生化机理 | 卡铂是一种铂类抗肿瘤药物，通过与邻近的鸟嘌呤残基形成链内交联来破坏DNA。肿瘤通过DNA错配修复(MMR)活性的丧失以及由此导致的程序性细胞死亡诱导的减少而获得对这些药物的抗性。 |
| 别名 | 卡波铂; 碳铂; 顺-二氨-1,1-环丁烷基二羟酸铂; 顺-二氨-1,1-环丁烷基二羧酸铂; 顺式-1,1-环丁烷二羧酸二氨铂;顺 - 二氨基（1，1-环丁烷二羧酸）铂 ;cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II); cis-Diammine(1,1-cyclobutanedicarboxylato) platinum;1,1-Cyclobutanedicarboxylatodiammineplatinum(II); cis-Diammine(1,1-cyclobutanedicarboxylato) platinum ; |
卡铂信息由上海阿拉丁生化科技股份有限公司为您提供，如您想了解更多关于卡铂报价、型号、参数等信息，欢迎来电或留言咨询。
注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途