BML-SA648-0200 200 µl
BML-SA648-0050 50 µl Endogenous opiates such as endorphins, endomorphins, and enkephalins, as well as opiate drugs (including morphine) exert their effects by binding to opioid receptors. Three "classic" types of opioid receptors have been identified: Mu (µ)-opioid (MOP) receptor, delta (δ)-opioid (DOP) receptor, and κ (κ)-opioid (KOP) receptor1. The opioid receptors belong to the G protein-coupled receptor superfamily. All three classic opioid receptors mediate opioid-induced analgesia.
Supraspinal analgesia is mainly mediated by the µ-opioid receptor, whereas µ-, δ-, and κ-receptors participate in the control of pain at the spinal level2. The opioid receptors also mediate the mood-altering properties of opioids2. The δ receptors are discretely distributed in the central nervous system, with a prominent gradient of receptor density from high levels in forebrain structures to relatively low levels in most hindbrain regions.
Product Specification
Alternative Name: DOR-1
Immunogen: Synthetic peptide corresponding to aa 2-18 of mouse DOP (δ-opioid receptor).
Source/Host: From rabbit.
Specificity: Recognizes rat DOP.
Application: Western Blot
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C
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