BML-T108-0005 5 mg Cytochalasin B is a cell-permeable fungal toxin which binds to the barbed end of actin filaments inhibiting both the association and dissociation of subunits. It causes the disruption of actin filaments and inhibition of actin polymerization. It also inhibits monosaccharide transport across cell membranes. inhibits glucose transport and platelet aggregation. Blocks adenosine-induced apoptotic body formation without affecting activation of endogenous ADP-ribosylation in leukemia HL-60 cells.
Product Specification
Formula: C29H37NO5
MW: 479.6
Purity: ≥98%
Appearance: white to off-white solid
CAS: 14930-96-2
Source/Host: Isolated from Drechslera dematoidea
Solubility: Soluble in methanol (20mg/ml).
Shipping: AMBIENT
Long Term Storage: -20°C
Hazard: TOXIC.
Handling: Protect from light.
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