BML-CA230-0025 25 mg
BML-CA230-0005 5 mg
A novel, selective inhibitor of receptor-mediated calcium entry. It inhibits receptor-mediated calcium entry in stimulated platelets (IC50=8-12µM) neutrophils and endothelial cells at concentrations which do not affect internal Ca2+ release. Note, in some cells SK&F 96365 can activate a novel Ca2+ entry pathway. Blocks TRPC3 and TRPC6 activation. Inhibits the histamine-induced formation of nitric oxide in human endothelial cells.
Product Specification
Alternative Name: SKF-96365 . hydrochloride
Formula: C22H26N2O3·HCl
MW: 402.9
Purity: ≥98% (TLC)
Appearance: White solid.
CAS: 130495-35-1
Solubility: Soluble in water (30mg/ml).
Shipping: AMBIENT
Long Term Storage: Ambient
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at room temperature. Stock solutions are stable for up to 3 months at -20°C.
Hazard: IRRITANT.
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