BML-EI252-0025 25 mg
BML-EI252-0005 5 mg RG-13022 is a non-phenolic tyrphostin analog, which inhibits the EGF receptor (IC50=5 µM) and PDGF receptor tyrosine kinases, and is long-acting. It inhibits EGF-stimulated HER14 cell proliferation (IC50=1 µM) as well as tumor growth in vivo. It inhibits both EGF- and PDGF-stimulated DNA synthesis in human glioma cell lines. RG-13022 is non-phenolic and therefore possesses less antioxidant activity than other tyrphostins.
Product Specification
Alternative Name: 3,4-Dimethoxy-α-(3-pyridyl)-(Z)-cinnamonitrile
Formula: C16H14N2O2
MW: 266.3
Purity: ≥99%
Appearance: White solid.
CAS: 136831-48-6
Solubility: Soluble at 25mg/ml in DMSO or 100% ethanol.
Shipping: AMBIENT
Long Term Storage: Ambient
Handling: Protect from light.
Store tightly sealed in the dark.
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