BML-EI347-0050 50 mg
BML-EI347-0010 10 mg DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models. DMOG also inhibits FIH (Factor Inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/kg). Is expected to act pro-angiogenic.
Product Specification
Alternative Name: DMOG, N-(Methoxyoxoacetyl)-glycine methyl ester
Formula: C6H9NO5
MW: 175.1
Purity: ≥99% (TLC)
Appearance: Off-white solid.
CAS: 89464-63-1
Solubility: Soluble in DMSO (>25mg/ml), 100% ethanol (>25mg/ml) or dimethyl formamide; soluble also in PBS, pH7.2 (10mg/ml).
Long Term Storage: Ambient
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at room temperature. Stock solutions are stable for up to 3 months at -20°C.
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