Adducin alpha antibody
Cat.#: S2412
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P35611
Mol Weight: 44.03kDa
Size: 100ul

Description
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq]

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:500-1:3000

Species Reactivity
Human

Other species have not been tested

Products Data 

 

Sample (30ug of whole cell lysate)
A: A431
10% SDS PAGE
diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded SG xenograft , using Alpha-adducin antibody at 1:100 dilution.

Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 198 of Human ADD1

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
ADD1 antibody, ADDA antibody, MGC3339 antibody, MGC44427 antibody, Alpha-adducin antibody, Erythrocyte adducin subunit alpha antibody