AK3 Antibody(C-term H38)
Cat.#: T3049
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P27144
Mol Weight: 25kDa
Size: 100ug

Description
AK3 is a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated.

Recommended Applications
WB, IHC, ELISA

Applications and Recommended Dilution Factors
WB: 1:100~500
IHC: 1:50~100
ELISA: 1:1,000

Species Reactivity
Human, Mouse

Products Data 

 

The anti-AK3 Pab is used in Western blot to detect AK3 in mouse kidney tissue lysate.
Western blot analysis of AK3 (arrow) using rabbit polyclonal AK3 Antibody (C-term H38) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AK3 gene (Lane 2) (Origene Technologies).

Specificity
This AK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194~223 amino acids from the C-terminal region of human AK3.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Alternative Names
AK4 antibody, AK3 antibody, AK3L1 antibody, AK3L2 antibody, MGC166959 antibody, Adenylate kinase isoenzyme 4, mitochondrial antibody, ATP-AMP transphosphorylase antibody, Adenylate kinase 3-like antibody

Description References
Van Rompay, A.R., et al., Eur. J. Biochem. 261(2):509-517 (1999).
Yoneda, T., et al., Brain Res. Mol. Brain Res. 62(2):187-195 (1998).
Xu, G., et al., Genomics 13(3):537-542 (1992).
Robson, E.B., et al., Cytogenet. Cell Genet. 32 (1-4), 144-152 (1982).