| Catalogue Number | ANT-191 |
| Synonyms | B1, S7, Bp35, MS4A2, LEU-16, MGC3969. |
| Type | Anti Human Recombinant. |
| Introduction | CD20 is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20 plays a role in the development and differentiation of B-cells into plasma cells. CD20 is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. |
| Description | Recombinant Anti Human CD20 monoclonal Antibody produced in CHO is a glycosylated polypeptide chain having a molecular mass of 80 kDa.
CD-20 is purified by proprietary chromatographic techniques. |
| Source | CHO. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Forrmulation | Lyophilized from a 0.2μm filtered concentrated (1mg/ml) solution in PBS, pH 7.4. |
| Solubility | It is recommended to reconstitute the lyophilized rAHuCD-20 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Stability | Lyophilized CD-20 Receptor although stable at room temperature for 3 weeks, should be stored desiccated below -18°C.
Upon reconstitution CD-20 Receptor should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles. |
| Purity | Greater than 95.0% as determined byAnalysis by RP-HPLC.
Analysis by SDS-PAGE gel. |
| Biological Activity | Fully biologically active when compared to standard determined by the apoptosis assay of Raji cell in vitro. |
| Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs,agricultural or pesticidal products, food additives or household chemicals. |
