ACOX1 Antibody(N-term)
Cat.#: T0815
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q15067
Mol Weight: 74kDa
Size: 100ug

Description
ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.

Recommended Applications
WB, ELISA

Applications and Recommended Dilution Factors
WB: 1:1,000
ELISA: 1:1,000

Species Reactivity
Human, Mouse

Products Data

Western blot analysis of anti-ACOX1 Pab in mouse liver lysate. Data is kindly provided by Hye Won Kang and Dr. McGrane at the Univ. of Connecticut (Storrs, CT).

Specificity
This ACOX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14~43 amino acids from the N-terminal region of human ACOX1.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Alternative Names
ACOX1 antibody, ACOX antibody, MGC1198 antibody, PALMCOX antibody, SCOX antibody, Peroxisomal acyl-coenzyme A oxidase 1 antibody, Palmitoyl-CoA oxidase antibody, Straight-chain acyl-CoA oxidase antibody

Description References
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Chu, R., et al., J. Biol. Chem. 270(9):4908-4915 (1995).
Aoyama, T., et al., Biochem. Biophys. Res. Commun. 198(3):1113-1118 (1994).
Fournier, B., et al., J. Clin. Invest. 94(2):526-531 (1994).
Varanasi, U., et al., Proc. Natl. Acad. Sci. U.S.A. 91(8):3107-3111 (1994).