ADCY2 Antibody(C-term)
Cat.#: T0914
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: Q08462
Mol Weight: 124kDa
Size: 100ug

Description
ADCY2 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate(cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

Recommended Applications
WB, IHC, ELISA

Applications and Recommended Dilution Factors
WB: 1:50~100
IHC: 1:10~50
ELISA: 1:1,000

Species Reactivity
Human

Products Data 

 

Western blot analysis of anti-ADCY2 Pab in Jurkat cell line lysates (35ug/lane). ADCY2(arrow) was detected using the purified Pab (1:60 dilution).
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ADCY2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specificity
This ADCY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 947~977 amino acids from the C-terminal region of human ADCY2.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Alternative Names
ADCY2 antibody, AC2 antibody, FLJ16822 antibody, FLJ45092 antibody, HBAC2 antibody, KIAA1060 antibody, MGC133314 antibody, Adenylate cyclase type 2 antibody, ATP pyrophosphate-lyase 2 antibody, Adenylate cyclase type II antibody, Adenylyl cyclase 2 antibody

Description References
Uhl,G.R.,Arch. Gen. Psychiatry 65 (6), 683-693 (2008)
Ludwig,M.G.,J. Recept. Signal Transduct. Res. 22 (1-4), 79-110 (2002)
Cote,M., J. Clin. Endocrinol. Metab. 86 (9), 4495-4503 (2001)