ADRB2 Antibody(S364)
Cat.#: T2195
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P07550
Mol Weight: 47kDa
Size: 100ug

Description
ADRB2, beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This protein is intronless.

Recommended Applications
WB, IHC, FC, ELISA

Applications and Recommended Dilution Factors
WB: 1:50~100
IHC: 1:50~100
FC: 1:10~50
ELISA: 1:1,000

Species Reactivity
Human

Products Data 

 

Western blot analysis of anti-ADRB2 Antibody (S364) in NCI-H460 cell line lysates (35ug/lane). ADRB2 (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human brain reacted with ADRB2 Antibody (S364), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specificity
This ADRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352~381 amino acids surrounding S364 of human BAR2.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Alternative Names
ADRB2 antibody, ADRB2R antibody, ADRBR antibody, B2AR antibody, BAR antibody, BETA2AR antibody, Beta-2 adrenergic receptor antibody, Beta-2 adrenoreceptor antibody

Description References
Kobilka B.K., Dixon R.A.F.Proc. Natl. Acad. Sci. U.S.A. 84:46-50(1987)
Emorine L.J., Marullo S.Proc. Natl. Acad. Sci. U.S.A. 84:6995-6999(1987)
Kobilka B.K., Frielle T.J. Biol. Chem. 262:7321-7327(1987)