5HT1B Receptor antibody
Cat.#: S0654
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P28222
Mol Weight: 43.57kDa
Size: 100ug

Description
The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of 4 main groups, 5-HT-1, 5-HT-2, 5-HT-3, and 5-HT4, subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM]

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:500-1:3000

Species Reactivity
Human

Other species have not been tested

Products Data

Sample(30ug of whole cell lysate)
A:HeLa S3
12% SDS PAGE
diluted at 1:500

Specificity
Synthetic peptide contain a sequence corresponding to a region within amino acids 249 and 313 of Human HTR1B

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
HTR1B antibody, 5-HT1B antibody, 5-HT1DB antibody, HTR1D2 antibody, HTR1DB antibody, S12 antibody, 5-hydroxytryptamine receptor 1B antibody, Serotonin receptor 1B antibody