AlaRS antibody
Cat.#: S2679
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P49588
Mol Weight: 106.83kDa
Size: 100ul

Description
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq]

Recommended Applications
WB

Applications and Recommended Dilution Factors
WB: 1:500-1:3000

Species Reactivity
Human

Other species have not been tested

Products Data

 
Sample (30ug of whole cell lysate)
A: A431
B: H1299
C: Hela
D: Hep G2
7.5% SDS PAGE
diluted at 1:1000

Specificity
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 461 and 693 of human AARS

Storage Condition and Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative. Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Purified by antigen-affinity chromatography.

Alternative Names
AARS antibody, CMT2N antibody, Alanyl-tRNA synthetase, cytoplasmic antibody, Renal carcinoma antigen NY-REN-42 antibody