ABCC1 Antibody(C-term)
Cat.#: T1520
Rabbit Polyclonal Antibody
Clone ID: polyclonal
Swiss Prot: P33527
Mol Weight: 172kDa
Size: 100ug

Description
ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC gene are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.

Recommended Applications
WB, FC, ELISA

Applications and Recommended Dilution Factors
WB: 1:50~100
FC: 1:10~50
ELISA: 1:1,000

Species Reactivity
Human

Products Data 

 

Western blot analysis of ABCC1 antibody (C-term) in Ramos cell line lysates (35ug/lane). ABCC1 (arrow) was detected using the purified Pab.
Flow cytometric analysis of NCI-H292 cells using ABCC1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specificity
This ABCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1254~1283 amino acids from the C-terminal region of human ABCC1.

Storage Condition and Buffer
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Alternative Names
ABCC1 antibody, ABC29 antibody, ABCC antibody, DKFZp686N04233 antibody, DKFZp781G125 antibody, GS-X antibody, MRP antibody, MRP1 antibody, Multidrug resistance-associated protein 1 antibody, ATP-binding cassette sub-family C member 1 antibody, Leukotriene C(4) transporter antibody

Description References
Siedlinski,M., Pharmacogenet. Genomics 19 (9), 675-684 (2009)