产地:usa
货号:C6762
CAS号: 14930-96-2 名称:Cytochalasin B from Drechslera dematioidea
别名: Phomin
分子量: 479.61
Biochem/physiol Actions
One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin,1 and in studies on cytokinesis.2 Probe for the two hexose-transport systems in rat L6 myoblasts.3
Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
相关类型 Actin Inhibitors and Probes, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics, Cell Signaling and Neuroscience, Chemical Structure Class, Cytoskeleton and Extracellular Matrix, Interferes with DNA Synthesis, Mechanism of Action, Miscellaneous, Mold, Toxins and Venoms
Quality Level PREMIUM
assay ≥98% (HPLC)
form powder
color white
solubility ethanol:soluble20 mg/mL
DMSO: soluble
storage temp. −20°C