Replaces Prod. #: ALX-270-115
Phospholipase A2 inhibitor (IC50=7 µM for purified guinea pig lung PLA2). Inhibits epinephrine-stimulated thromboxane production in human platelets (86% at 3.5µM). Also blocks insulin secretion in pancreatic islets in response to glucose. Disrupts membrane tubule-mediated reassembly and maintenance of the Golgi complex.
Product Specification
Alternative Name: 2-(p-Amylcinnamoyl)amino-4-chlorobenzoic acid
Formula: C21H22ClNO3
MW: 371.9
Purity: ≥98% (TLC)
Appearance: Off-white to yellow solid.
CAS: 99754-06-0
Solubility: Soluble in DMSO (25mg/ml, warm) or 100% ethanol (10mg/ml, warm).
Shipping: AMBIENT
Long Term Storage: +20°C
Use/Stability: Stable for at least 2 years after receipt when stored at +20°C. Stock solutions are stable for up to 3 months at -20°C.
Handling: Do not freeze.
Protect from light.