Product Specification
Alternative Name: N-[2-(Methylamino)ethyl]-5-isoquinolinesulfonamide . 2HCl
Formula: C12H15N3O2S·2HCl
MW: 338.3
Purity: 99% (TLC)
Appearance: White to off-white solid.
CAS: 113276-94-1
Solubility: Soluble in DMSO (25mg/ml) and ethanol/water (1:1, 25mg/ml).
Shipping: AMBIENT
Long Term Storage: +4°C
Use/Stability: Store, as supplied, at 0-4°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Replaces Prod. #: ALX-270-067
H-8 inhibits PKA and PKG selectively over PKC and MLCK (IC50’s=1.2μM, 0.48μM, 15μM and 68μM respectively). It also inhibits myosin light chain kinase.