耗材描述
Product Specification
Alternative Name: PEA
Formula: C18H37NO2
MW: 299.5
Purity: ≥98% (TLC)
Appearance: White solid.
CAS: 544-31-0
Solubility: Soluble in DMSO or 100% ethanol.
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: +4°C
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at 0-4°C. Stock solutions are stable for up to 3 months at -20°C.
Replaces Prod. #: ALX-300-146
Endogenous cannabinoid. Weak ligand of CB1 (Ki=23.8µM) and CB2 (Ki=13.9µM) receptor. Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.1µM). Immunosuppressant, anti-inflammatory, anti-nociceptive and anti-convulsant in vivo. The exact mode of action has not yet been revealed. It has been suggested that PEA: i) binds to a yet to be discovered cannabinoid receptor similar to CB2; ii) administered in vivo elicits the synthesis of endogenous agonists of CB2; iii) acts as an "entourage" compound by enhancing the activity and/or by influencing the turnover of endogenous agonists of CB2, possibly but not uniquely, by inhibiting their degradation.