Replaces Prod. #: ALX-630-080
The A promoter (S1) of pertussis toxin possesses both NAD+ glycohydrolase and ADP-ribosyltransferase actitivies, but is unable to penetrate cells in the absence of B oligomer. It is, however, as effective as native pertussis toxin in catalyzing ADP-ribosylation in broken cell preparations.
Product Specification
Alternative Name: Islet-activating protein A protomer, PTX A protomer
MW: 28 kDa
Purity: ≥ 99%
Formulation: Lyophilized.
Source/Host: From Bordetella pertussis.
Long Term Storage: +4°C
Use/Stability: This preparation is lyophilized, aseptically packaged and sealed under vacuum. Store at 4°C prior to reconstitution. Do not freeze. The lyophilized preparation will remain active for at least one year. After reconstitution with sterile water this product should remain active for at least four weeks if stored at 4°C.
Hazard: TOXIC.
Handling: Do not freeze.
Miscellaneous/General: The A protomer (S-1) of pertussis toxin possesses both NAD+ glycohydrolase and ADP-ribosyltransferase activities but is unable to penetrate cells in the absence of B oligomer1. It is however, as effective as native pertussis toxin in catalyzing ADP-ribosylation in broken cell preparations.