Product Specification
Source/Host: Synthetic.
Long Term Storage: +4°C
Miscellaneous/General: Dsk2p from Saccharomyces cerevisiae belongs to a class of proteins that contain a ubiquitin-like (UbL) domain at the N-terminus together with a ubiquitin-associated (UBA) domain at the C-terminus. It has been shown that the C-terminal UBA domain of Dsk2p binds to K48-linked polyubiquitin chains and that the N-terminal Ubl domain of Dsk2p interacts with the proteasome. The Dsk2 UBA domain may therefore be particularly useful for capturing the totality of ubiquitin-modified proteins from complex protein mixtures.