Chromogranin A (CgA) is a prohormone which is proteolytically processed in neurons prior to axonal transport. The differential expression of chromogranin A fragments in neuronal populations suggests distinct functional roles for each CgA-derived peptide. Immunohistochemical localization of CgA has been used as amarker for the identification and prognostic assessment of neuroendocrine tumours and CgA has also been reported to be a component of senile plaques in the brains of demented individuals.
Product Specification
Alternative Name: CgA
Formulation: Liquid. Antiserum containing 0.1% sodium azide.
Immunogen: Synthetic peptide (Leu-Pro-Val-Asn-Ser-Pro-Met-Asn-Lys-Gly-Asp-Thr-Glu-Val-Met-Lys-Cys) corresponding to a portion of N-terminal human CgA.
Source/Host: From sheep.
Specificity: Recognizes human, rat and cow CgA.
Application: Immunohistochemistry
Western Blot
Shipping: SHIPPED ON BLUE ICE
Long Term Storage: -20°C